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NAD+ and Aging: The Test That Reveals Your Cellular Energy Health

NAD+ and Aging: The Test That Reveals Your Cellular Energy Health

NAD⁺ (nicotinamide adenine dinucleotide) is the spark plug of your cells. Without it, your mitochondria — the energy factories of your body — can't function. DNA repair slows. Inflammation rises. And aging accelerates.

By the time you're 50, your NAD⁺ levels may have dropped by more than 50%. If you’re feeling chronically tired, foggy, or aging faster than you’d like, your NAD⁺ status might be the missing piece.

⚡ What Is NAD⁺?

NAD⁺ is a coenzyme found in every cell. It’s essential for:

  • Cellular energy (ATP) production
  • DNA repair and cellular maintenance
  • Immune system regulation
  • Sirtuin activation – longevity-linked genes that protect against aging

📉 Why NAD⁺ Declines With Age

Your body naturally produces less NAD⁺ as you age. But modern lifestyles accelerate this decline:

  • Chronic stress
  • Alcohol and tobacco use
  • Poor sleep or circadian disruption
  • Inflammation and metabolic dysfunction

⚠️ Symptoms of Low NAD⁺

  • Fatigue and low stamina
  • Brain fog or slower thinking
  • Delayed recovery after stress or exercise
  • Signs of premature aging

Because NAD⁺ supports over 500 enzymatic reactions, its decline affects everything from metabolism to cognition.

🧪 How to Measure Your NAD⁺ Status

The NAD⁺ Index Test provides a complete picture of your cellular energy and niacin (vitamin B3) metabolism. It measures:

  • NAD⁺ and NADH – the oxidized and reduced forms of the core coenzyme
  • NADP⁺ and NADPH – involved in antioxidant defense and biosynthesis
  • NAD/NADH and NADP/NADPH ratios
  • Nicotinamide (NAM) and Nicotinic Acid (NA) – vitamin B3 metabolites

This comprehensive test helps identify whether you're depleted, balanced, or at risk of dysfunction — all from a dried blood spot sample at home.

💊 How to Boost NAD⁺ Naturally

  • NMN or NR supplements – direct NAD⁺ precursors
  • Exercise – boosts NAD⁺ biosynthesis pathways
  • Intermittent fasting – activates sirtuins and NAD⁺ production
  • Good sleep – restores mitochondrial efficiency
  • Minimising alcohol and processed sugar

However, response to supplementation varies — that’s why testing first is key.

🎯 Why Test NAD⁺ Levels?

NAD⁺ supplements are expensive. Testing gives you data to:

  • See if you actually need supplementation
  • Tailor your dose for efficiency and safety
  • Track how your levels change with supplements, fasting, or training

Don’t guess. Test. Rebuild your cellular engine from the inside out with our NAD⁺ Index Test.


🔎 FAQs About NAD⁺ and the NAD⁺ Index Test

What’s the difference between NAD⁺ and NADH?

NAD⁺ is the oxidized form, while NADH is the reduced form. They work as a pair, enabling energy transfer in your cells. Balanced ratios are key for mitochondrial health.

Can I test NAD⁺ at home?

Yes. The NAD⁺ Index Test is a dried blood spot test you complete at home and return by post. It’s analysed using LC-MS/MS for high accuracy.

What does the NAD/NADH ratio tell me?

This ratio is a key marker of cellular redox status and mitochondrial health. A low ratio can signal energy dysfunction or oxidative stress.

Do I need to stop supplements before testing?

If you're already taking NMN or NR, continue if you want to see your current levels. If you're establishing a baseline, pause for 5–7 days unless advised otherwise by a practitioner.

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