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Glutathione At Home Test

Track Your Body’s Antioxidant Status and Redox Balance

Glutathione Index Test

The Glutathione Index Test is a unique at-home blood test that measures one of the most important markers of your cellular health: your glutathione status. Glutathione is often called the master antioxidant, produced by your body to neutralize free radicals, detoxify cells, and maintain mitochondrial function. Unlike standard antioxidant tests that only assess total levels, this test evaluates both reduced glutathione (GSH) and oxidised glutathione (GSSG) to calculate your GSH:GSSG ratio, a gold-standard biomarker of oxidative stress and redox balance.

If you’re serious about longevity, immune function, or cellular health, measuring your glutathione status is one of the most powerful ways to assess how well your body is coping with internal and external stressors. A low GSH:GSSG ratio suggests your antioxidant defenses are overwhelmed, increasing the risk of inflammation, tissue damage, and accelerated aging.

With just a few drops of blood collected at home using a simple dried blood spot (DBS) card, this lab-based test gives you clinical-grade insights—no clinic visit required.

Whether you’re managing chronic conditions, supporting detox pathways, tracking recovery, or optimising performance and healthy aging, this test reveals what your blood isn’t saying in standard panels.

Why Test Glutathione Index?

Glutathione is your body’s first line of defense against oxidative damage. It plays a central role in:

  • Detoxifying toxins and heavy metals
  • Supporting immune health and inflammation balance
  • Regenerating other antioxidants (like vitamins C and E)
  • Maintaining mitochondrial energy production
  • Slowing the cellular aging process

A low Glutathione Index may reflect oxidative stress or a depletion of antioxidant capacity. This can result from chronic inflammation, poor diet, lack of sleep, overtraining, illness, or environmental toxin exposure.

How to Improve Your Glutathione Index

You can naturally support your glutathione levels and redox balance through targeted diet, lifestyle changes, and supplementation strategies:

  • Exercise regularly: Moderate-intensity physical activity has been shown to increase glutathione production and improve antioxidant enzyme activity.
  • Eat glutathione-boosting foods: Include sulfur-rich foods like broccoli, cauliflower, garlic, onions, and Brussels sprouts. These help your body produce more glutathione naturally.
  • Support with antioxidant nutrients: Vitamins C and E, selenium, and zinc help regenerate and stabilise glutathione. Alpha-lipoic acid and CoQ10 also enhance redox cycling.
  • Avoid alcohol and processed foods: These increase oxidative stress and may deplete your natural glutathione reserves over time.
  • Supplement precursors when needed: N-acetylcysteine (NAC), liposomal glutathione, milk thistle (silymarin), and whey protein are all proven to support glutathione synthesis and recycling.
  • Prioritise sleep and manage stress: Oxidative stress increases with poor sleep and chronic stress. Aim for quality rest and include stress-reducing practices like breathwork, meditation, or yoga.
  • Monitor and retest: Recheck your Glutathione Index every 6–12 weeks, especially when making changes to your diet or supplement routine. This helps track how your body responds over time.
What Is a Healthy NAD+ Index Range?
  • GSH (Reduced Glutathione): 400–900 μmol/L
  • GSSG (Oxidized Glutathione): 10–30 μmol/L
  • GSH:GSSG Ratio (Glutathione Index): Optimal: ≥700, Suboptimal: 400–700 & Low: <400 (suggests elevated oxidative stress)

A high Glutathione Index (GSH:GSSG ratio) indicates strong antioxidant capacity and low oxidative stress. A low ratio may reflect inflammation, cellular aging, or toxin exposure. This balance is one of the best markers of redox status and biological resilience.

Backed by Science
  • Wu et al. (2004): Demonstrated that a lower GSH:GSSG ratio is a sensitive marker of oxidative stress and cellular dysfunction, often preceding signs of chronic disease.
  • Jones et al. (2002): Identified the redox potential of the GSH/GSSG couple as a key determinant of cellular signaling, immune modulation, and apoptosis.
  • Pizzorno (2014): Reviewed glutathione as the most important antioxidant in human physiology—critical for detoxification, mitochondrial health, and immune resilience.
  • Sekhar et al. (2011): Found that glutathione deficiency is common in aging and metabolic syndrome, and supplementation with NAC can restore redox balance.

These studies support the clinical value of measuring both reduced and oxidized glutathione, and using the GSH:GSSG ratio as a sensitive biomarker of oxidative stress, detox capacity, and biological aging.

The Glutathione Index Test empowers you to track these changes and personalize your health strategy with confidence.

Key Benefits
  • Measure oxidative stress at the source – Evaluate your body’s antioxidant capacity and redox balance with the gold-standard GSH:GSSG ratio
  • Track supplement effectiveness – See whether NAC, alpha-lipoic acid, or glutathione supplementation is actually improving your antioxidant status
  • Support detox and immune function – Understand how well your body is neutralizing free radicals and eliminating toxins
  • Guide anti-aging and longevity strategies – Use objective data to assess cellular resilience and inform lifestyle changes
  • Easy at-home collection – Just a few drops of blood via finger-prick, no venous draw or clinic visit required
What's Measured?
  • Reduced Glutathione (GSH) – the active, protective form
  • Oxidised Glutathione (GSSG) – the “used” form after neutralizing free radicals
  • GSH:GSSG Ratio – a gold-standard marker of oxidative stress and redox balance
Who Should Use This Test?

This test is ideal for people who:

  • Want to monitor oxidative stress and recovery
  • Are focused on healthy aging or detoxification
  • Take antioxidants (like NAC, alpha lipoic acid, CoQ10) and want to track their impact
  • Are managing chronic inflammation or metabolic stress
  • Are athletes or biohackers monitoring redox balance
What's Included?
  • Dried blood spot (DBS) collection card
  • Lancets, alcohol swab, gauze, bandage
  • Prepaid return envelope and instructions
  • Accredited lab analysis + secure online results
 
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FAQs

Why test Glutathione Index?

Glutathione is the body’s master antioxidant, essential for neutralizing free radicals, supporting detoxification, maintaining mitochondrial health, and regulating immune response. It exists in two forms—reduced (GSH) and oxidised (GSSG)—and the ratio between them (GSH:GSSG) is a well-established marker of oxidative stress and cellular resilience.

However, glutathione levels decline with age, stress, toxicity, chronic inflammation, and poor nutrition. This can compromise detox capacity, impair recovery, and accelerate aging.

Testing your Glutathione Index offers a clear view into how well your antioxidant system is functioning—and whether interventions like supplements (e.g. NAC, liposomal glutathione) or lifestyle changes are improving redox balance.

Do I need to fast?

No, fasting is not required. You can take the Glutathione Index Test at any time of day. However, if you're taking antioxidant supplements like N-acetylcysteine (NAC),glutathione, alpha-lipoic acid, or selenium, it’s best to avoid them for 12–24 hours prior to testing for the most accurate baseline reading.

What is an optimal Glutathione Index level?

There are no globally defined clinical cutoffs for glutathione, but based on current research and reference ranges, these general guidelines apply:

  • GSH (Reduced Glutathione): Active form that protects cells
  • GSSG (Oxidised Glutathione): Used form after neutralising oxidative damage
  • Glutathione Index (GSH:GSSG Ratio):

A high ratio indicates robust antioxidant capacity and redox balance. A lower ratio may suggest increased oxidative burden, chronic inflammation, or poor detoxification capacity. Your report includes reference ranges and personalised interpretation.

Is this test suitable for vegetarians or vegans?

Yes. This test is completely diet-agnostic and safe for individuals following vegetarian, vegan, or plant-based diets. It measures your body’s natural antioxidant status—regardless of your food sources—and can help you assess whether your current diet or supplement routine is supporting your redox health effectively.

When is the best time to test?

You can take the Glutathione Index Test at any time of day. Fasting is not required.

However, for consistent tracking over time, try to collect samples under similar conditions (e.g. time of day, supplement use). If you take antioxidant supplements such as NAC, glutathione, alpha-lipoic acid, or selenium, you may wish to avoid them for 12–24 hours beforehand to get a baseline reading—unless you want to measure their current effect.

How can I increase my Glutathione levels?

Glutathione can be naturally increased through:

  • Precursors: N-acetylcysteine (NAC), alpha-lipoic acid, glycine, and selenium support glutathione synthesis.
  • Lifestyle: Regular exercise, quality sleep, and stress management all help maintain healthy glutathione levels.
  • Diet: Focus on sulfur-rich foods like garlic, onions, broccoli, Brussels sprouts, and protein sources such as fish and eggs.
  • Supplements: Liposomal glutathione, whey protein, milk thistle, and antioxidant blends may support redox balance—especially under stress or toxicity.

Re-test after 6–12 weeks to track improvements and assess how your body is responding.

Is the test safe and easy to do at home?

Yes. The test uses a simple dried blood spot (DBS) collection method — just a few drops from your fingertip, no clinic visit or blood draw required. All supplies and step-by-step instructions are included in the kit.

What does the test include

Your kit includes everything you need to collect and return your sample from home: a dried blood spot (DBS) collection card, full instructions, and a return envelope. You’ll also receive a secure lab report with your Glutathione Index results and reference ranges.

How accurate is the Glutathione Index test from a dried blood spot?

Our Glutathione Index Test is analysed using liquid chromatography–mass spectrometry (LC-MS/MS)—the same gold-standard technology used in clinical research and hospitals. This highly sensitive and specific method allows us to precisely quantify both reduced glutathione (GSH) and oxidised glutathione (GSSG) from just a few drops of blood collected via a simple dried blood spot (DBS) card.

Even though the sample is collected at home, the accuracy is on par with venous blood draws processed in clinical settings. DBS samples analysed via LC-MS/MS have been shown to provide clinically valid and reproducible glutathione values—giving you and your healthcare provider meaningful insights into your redox balance and oxidative stress status.

How long until I get results?

Once your sample is received by the lab, your results will be available within 3-5 business days.